Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics

Effects of brimonidine tartrate 0.2 and 0.15% ophthalmic solution on the static and dynamic pupil characteristics

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AimsTo investigate the differences between 0.2 and 0.15% brimonidine tartrate eye drops for anti-mydriatic effects and the optical quality under different light conditions.MethodsThis prospective study involved 80 consecutive high myopia patients undergoing implantation of a V4c ICL.The patients were randomly instilled with brimonidine 0.

2 and 0.15% 2 weeks postoperatively.Visual quality, pupil center, pupil size, and refraction under different light conditions were measured before and 0.5 h after brimonidine administration.A symptom questionnaire was also evaluated.

ResultsThere was no statistical difference in the static and dynamic teucrium cossonii majoricum pupil diameters and velocity after LS between the two groups (p > 0.05).The 0.2% group had significant changes in pupil center before and after treatment, while there was no obvious movement of the 0.15% group under all illumination condition (p > 0.

05).The OSI after treatment of the 0.15% group was lower than that of 0.2% group (p = 0.012).

The PVA9% and PVA100% of the 0.15% group was higher than that of 0.2% group in the dark (p = 0.009, p = 0.012).

The HOA RMS of the 0.15% group was lower than that of 0.2% group (p = 0.016).The QIRC score in the 0.

15% group was significantly higher than that in the 0.2% group (p = 0.043).Conclusion0.15 and 0.

2% brimonidine tartrate eye drops had essie cause and reflect similar anti-mydriatic ability, while 0.15% group had better visual quality than 0.2% concentration, and hardly introduced pupil shift.0.15% brimonidine tartrate eye drops may be more suitable for patients with nocturnal glare symptoms in the early postoperative period after ICL implantation.